Thermo Fisher Scientific RASGRP3 Monoclonal Antibody (OTI5D2), TrueMAB
RASGRP3 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot에 최적화되어 있습니다. 인간 유래 재조합 단백질(AA 380-690)을 면역원으로 사용했으며, 동결건조 형태로 제공됩니다. 연구용으로 신호전달 및 RAS 활성화 연구에 적합합니다.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5D2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 380–690 of human RASGRP3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Members of the RAS subfamily of GTPases act as GTP/GDP-regulated switches in signal transduction, cycling between inactive GDP-bound and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RASGRP3, activate RAS by promoting GTP acquisition, linking cell surface receptors to RAS activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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