Thermo Fisher Scientific Catenin alpha-1 Polyclonal Antibody
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카탈로그 번호 | CAS 번호 | 설명 | 상태 | 재고 | 단위 | 판매가 | 할인가 | 가격(VAT포함) | 수량 / 장바구니 / 찜 |
PA528345 | - | Thermo Fisher Scientific PA528345 Catenin alpha-1 Polyclonal Antibody 100 ul pk | 재고문의 | pk | 663,000원 | - | 729,300원 |
다른 상품 둘러보기
Applications
Tested Dilution
Publications
Western Blot (WB)
1:500-1:10,000
Immunohistochemistry (Paraffin) (IHC (P))
1:100-1:1,000
Immunoprecipitation (IP)
Assay-dependent
Product Specifications
Species Reactivity
Human, Mouse, Rat
Host/Isotype
Rabbit / IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fragment corresponding to a region within amino acids 511 and 906 of Human alpha Catenin if (typeof window.$mangular === undefined
|| !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{
targetFamily:
Catenin alpha-1,
uniProtId:
P35221-1,
ncbiNodeId:
9606,
antigenRange:
511-906,
antigenLength:
906,
antigenImageFileName:
PA5-28345_Catenin_alpha-1_P35221-1_Rabbit.svg,
antigenImageFileNamePDP:
PA5-28345_Catenin_alpha-1_P35221-1_Rabbit_PDP.jpeg,
sortOrder:
1}\]
; $mangular.isB2BCMGT = false
; $mangular.isEpitopesModalImageMultiSizeEnabled = true
;
View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.01% thimerosal, 0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2545821
Product Specific Information
Recommended positive controls: 293T, A431, mouse brain, rat brain.
Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (93%), Xenopus laevis (96%), Rabbit (100%), Rhesus Monkey (99%), Bovine (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Can associate with both E- and N-cadherins. Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions. In contrast, cortical actin was found to be much more dynamic than E-cadherin/catenin complexes and CTNNA1 was shown not to bind to F-actin when assembled in the complex suggesting a different linkage between actin and adherence junctions components. The homodimeric form may regulate actin filament assembly and inhibit actin branching by competing with the Arp2/3 complex for binding to actin filaments. May play a crucial role in cell differentiation.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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