Thermo Fisher Scientific FABP7 Monoclonal Antibody (2A84)
FABP7 단백질을 인식하는 마우스 단클론 항체로, Western blot, IHC, ICC/IF에 적합합니다. 인간, 마우스, 랫트 시료에 반응하며, 단백질 A/G로 정제된 액상 포맷입니다. 단기 4°C, 장기 -20°C 보관을 권장합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Immunohistochemistry (IHC) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2A84 |
| Immunogen | Recombinant full length human FABP7 expressed in and purified from E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage buffer | PBS with 50% glycerol |
| Contains | 5 mM sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2942380 |
Target Information
FABP7 was initially isolated from a human fetal brain cDNA library and its mRNA is expressed in adult brain and muscle tissues at low levels. The protein encoded by this gene belongs to the fatty acid binding protein (FABPs) family, a group of small, highly conserved cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs are thought to play roles in fatty acid uptake, transport, and metabolism.
FABP7 is a downstream gene of the Pax6 transcription factor and is suggested to be essential for the maintenance of neuroepithelial cells during early cortical development. It is frequently expressed in melanomas, and down-regulation of FABP7 through RNAi expression could reduce in vitro cell proliferation and Matrigel invasion, suggesting FABP7 may be a potential target for diagnostic and therapeutic tool development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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