Thermo Fisher Scientific Parvalbumin Monoclonal Antibody (3C9)
Parvalbumin 단백질을 인식하는 Mouse monoclonal antibody (Clone 3C9). Western blot, IHC, ICC/IF에 사용 가능. 다양한 종(Bovine, Human, Mouse 등)에 반응. Protein A/G 정제, 1 mg/mL 농도, PBS+50% glycerol 보존. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1:1,000–1:5,000 |
| Immunocytochemistry (ICC/IF) | 1:1,000–1:5,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Horse, Human, Mouse, Pig, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3C9 |
| Immunogen | Full-length recombinant human parvalbumin protein expressed in and purified from E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage buffer | PBS with 50% glycerol |
| Contains | 5 mM sodium azide |
| Storage conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2942392 |
Target Information
Parvalbumin (PV) is a calcium-binding protein expressed in specific muscle fibers and fast-firing neurons. PV consists of a single, unbranched chain of amino acids and belongs to the EF-hand protein family. It plays a role in calcium decay during muscle contraction and relaxation cycles, showing a correlation between relaxation rate and parvalbumin concentration. PV is also expressed in GABAergic interneurons that help maintain excitation–inhibition balance in the cortex and hippocampus. In amyotrophic lateral sclerosis (ALS), PV immunoreactivity is absent from neuron populations lost early in disease progression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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