Thermo Fisher Scientific PER1 Polyclonal Antibody
PER1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC/IF에 적합합니다. 인간, 마우스, 랫트 반응성을 가지며, 항원 친화 크로마토그래피로 정제되었습니다. 세포 핵 및 세포질에서 PER1 단백질 검출에 유용합니다.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific PER1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human PER1 protein (aa 751–850) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.4, with 50% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2913370 |
Product Specific Information
- Positive Control: 293T cell lysate, HeLa cell lysate, Daudi cell lysate, mouse pancreas tissue lysate, rat brain tissue lysate, HeLa, rat kidney tissue
- Subcellular Location: Nucleus, Cytoplasm
Target Information
Circadian rhythmicity is a fundamental biological property observed across diverse organisms, including animals, plants, and fungi. In mammals, endogenous biological clocks are regulated by a protein-mediated autoregulatory feedback loop involving members of the bHLH-PAS (PER-ARNT-SIM) transcription factor family.
CLOCK-ARNT3 heterodimers bind to E-box regulatory elements (CACGTG) to stimulate gene transcription. PER proteins, together with TIM, negatively regulate their own transcription by inhibiting the CLOCK-BMAL1 transactivation complex, thereby maintaining circadian oscillation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.