Thermo Fisher Scientific HNF1A Recombinant Rabbit Monoclonal Antibody (2Z4Z0)
HNF1A 단백질을 인식하는 토끼 단클론 항체로, 인간, 마우스, 랫트 시료에 반응합니다. IHC(P) 및 ELISA에 적합하며, HEK293 세포에서 발현된 재조합 항체입니다. 고순도의 Affinity chromatography 정제 제품으로, -20°C에서 보관합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 2Z4Z0 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 31–128 of human HNF1 alpha (NP_000536.6) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.08 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_3094272 |
Product Specific Information
Immunogen sequence:
GEPGPYLLAG EGPLDKGESC GGGRGELAEL PNGLGETRGS EDETDDDGED FTPPILKELE NLSPEEAAHQ KAVVETLLQE DPWRVAKMVK SYLQQHNI
Target Information
This gene is expressed ubiquitously with higher levels in fetal than in adult tissues. It encodes a protein sharing 93% sequence identity with the mouse protein. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene is mapped to the 165 kb WHS critical region and may play a role in the phenotype of WHS or Pitt-Rogers-Danks syndrome. The encoded protein can react with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting potential use in specific immunotherapy for various cancers. It is also a member of the NELF (negative elongation factor) protein complex that regulates RNA polymerase II transcription elongation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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