
Thermo Fisher Scientific Phospho-Thyrotropin-Releasing Hormone Receptor 1 (Thr371) Polyclonal Antibody
인간 TRH1 Thr371 인산화 부위에 특이적인 폴리클로날 항체로, Western blot에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 액상 형태로 제공됩니다. 단기 4°C, 장기 -20°C 보관이 권장됩니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human TRH1 around the phosphorylation site of Thr371 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Dulbecco’s PBS, pH 7.4 |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
TRH-R is a 398 amino acid integral membrane protein with six transmembrane domains and belongs to the G-protein coupled receptor 1 family.
It acts as a receptor for the signaling hormone TRH and activates the inositol phospholipid-calcium-protein kinase C transduction pathway upon binding with TRH.
Reports suggest that TRH-R functions as a neurotransmitter and neuro regulator controlling dimerization of the TRH receptor and potentiating hormone-induced receptor trafficking.
It is widely expressed in the thyrotroph cells of the anterior pituitary.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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