Thermo Fisher Scientific UT, Urotensin Receptor Polyclonal Antibody
Urotensin 수용체를 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, Western blot에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 액상 형태로 제공됩니다. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
- Western Blot (WB): 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide representing part of the carboxyl-terminal tail of human UT |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Dulbecco’s PBS, pH 7.4 |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
The Urotensin-II receptor is highly expressed in the heart and pancreas, as well as in arteries and smooth muscle. Lower transcript levels are found in the brain, particularly in the thalamus and superior occipital gyrus.
G-protein Coupled Receptors (GPCRs) form one of the largest families of signaling molecules, sharing a structural motif of seven membrane-spanning helices. These receptors exist in active and inactive forms, influenced by various activating ligands that trigger downstream signaling via G-proteins.
GPCR regulation plays a critical role in cellular physiology and is a major focus of pharmacological research, leading to the development of several blockbuster GPCR-targeted drugs such as Zyprexa (Eli Lilly) and Claritin (Schering-Plough).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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