
Thermo Fisher Scientific Phospho-Thyrotropin-Releasing Hormone Receptor 1 (Ser364, Thr365) Polyclonal Antibody
인간 TRH1 단백질의 Ser364/Thr365 인산화 부위를 인식하는 폴리클로날 항체. Western blot에 최적화되어 있으며, 항원 친화 크로마토그래피로 정제됨. 1 mg/mL 농도의 액상 형태로 제공되며, 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): 1:1,000 dilution tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human TRH1 around the phosphorylation site of Ser364/Thr365. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Dulbecco’s PBS, pH 7.4 |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
TRH-R is a 398 amino acid integral membrane protein with six transmembrane domains and belongs to the G-protein coupled receptor 1 family. It acts as a receptor for the signaling hormone TRH and activates the inositol phospholipid-calcium-protein kinase C transduction pathway upon binding with TRH. Reports suggest that TRH-R is a neurotransmitter and neuro regulator that controls dimerization of the TRH receptor and potentiates hormone-induced receptor trafficking. It is known to be widely expressed in the thyrotroph cells of the anterior pituitary.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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