Thermo Fisher Scientific Human IL-24 Recombinant Protein, PeproTech
Recombinant Human IL-24 단백질로, CHO 세포에서 발현된 18.9 kDa His-tag 단백질입니다. ≥95% 순도, Endotoxin <1 EU/µg 수준으로 정제되었습니다. JAK/STAT 신호경로 연구 및 암세포 성장 억제 기전 연구에 적합합니다.
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Applications
- Functional Assay (Assay-dependent)
- In vitro Assay
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Human |
| Published Species | Human |
| Expression System | CHO cells |
| Amino Acid Sequence | QEFHFGPCQV KGVVPQKLWE AFWAVKDTMQ AQDNITSARL LQQEVLQNVS DAESCYLVHT LLEFYLKTVF KNYHNRTVEV RTLKSFSTLA NNFVLIVSQL QPSQENEMFS IRDSAHRRFL LFRRAFKQLD VEAALTKALG EVDILLTWMQ KFYKLHHHHH H |
| Tag | His-tag |
| Molecular Weight | 18.9 kDa |
| Class | Recombinant |
| Type | Protein |
| Purity | ≥ 95% by SDS-PAGE gel and HPLC analyses |
| Endotoxin Concentration | <1 EU/µg |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Purification | Purified |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient |
Product Specific Information
- Catalog number 200-35-1MG is supplied as 2 × 500 µg (200-35-500UG).
- Recombinant Human IL-24 is an 18.9 kDa glycoprotein containing 161 amino acid residues, including a C-terminal His-tag.
- This product is shipped at ambient temperature.
- For storage, handling, and reconstitution information, please refer to the lot-specific Certificate of Analysis.
Target Information
Interleukin 24 (IL-24), also known as melanoma differentiation-associated gene-7 (mda-7), encodes a secreted protein homologous to the interleukin 10 (IL-10) cytokine family.
Human IL-24 is secreted by activated peripheral blood mononuclear cells and binds two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2, activating the JAK/STAT signaling pathways.
Mda-7/IL-24 selectively induces growth suppression, apoptosis, and radiosensitization in malignant gliomas in a p53-independent manner.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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