Thermo Fisher Scientific Actin, Muscle Specific Monoclonal Antibody (HHF35)
근육 특이적 액틴 단백질을 인식하는 HHF35 단클론 항체. Western blot, IHC, ICC 등 다양한 응용에 사용 가능. 인간, 생쥐, 랫트 반응성. 액상 형태로 안정적이며 장기 보관 가능. 연구용으로 적합.
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Thermo Fisher Scientific Actin, Muscle Specific Monoclonal Antibody (HHF35)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–10 µg/mL |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | HHF35 |
| Immunogen | A synthetic peptide corresponding to the internal segment of human Actin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: Muscle
- Cellular location: Cytoplasmic
Target Information
The product encoded by this gene belongs to the actin family of proteins, which are highly conserved and play key roles in cell motility, structure, and integrity.
Alpha, beta, and gamma actin isoforms have been identified:
- Alpha actins: Major constituent of the contractile apparatus in muscle.
- Beta and gamma actins: Involved in regulation of cell motility.
This antibody targets alpha actin, found in skeletal muscle.
Mutations in the corresponding gene are associated with:
- Nemaline myopathy type 3
- Congenital myopathy with excess thin myofilaments
- Congenital myopathy with cores
- Congenital myopathy with fiber-type disproportion
These conditions result in muscle fiber defects.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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