Thermo Fisher Scientific Carbonic Anhydrase III Polyclonal Antibody
Carbonic Anhydrase III 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, ICC/IF, ELISA 등에 적합하며 Human, Mouse, Rat 반응성. 고순도 Affinity Chromatography 정제, PBS/glycerol buffer 저장, 연구용 전용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–260 of human CA3 (NP_005172.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.92 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2913791 |
Product Specific Information
- Positive test controls: Mouse kidney, Mouse lung, Mouse skeletal muscle
- Localization: Cytoplasm
Immunogen sequence:
MAKEWGYASH NGPDHWHELF PNAKGENQSP VELHTKDIRH DPSLQPWSVS YDGGSAKTIL NNGKTCRVVF DDTYDRSMLR GGPLPGPYRL RQFHLHWGSS DDHGSEHTVD GVKYAAELHL VHWNPKYNTF KEALKQRDGI AVIGIFLKIG HENGEFQIFL DALDKIKTKG KEAPFTKFDP SCLFPACRDY WTYQGSFTTP PCEECIVWLL LKEPMTVSSD QMAKLRSLLS SAENEPPVPL VSNWRPPQPI NNRVVRASFK
Target Information
Carbonic anhydrase III (CAIII) is a member of a multigene family encoding carbonic anhydrase isozymes. These metalloenzymes catalyze the reversible hydration of carbon dioxide and are differentially expressed across various cell types.
CA3 expression is tissue-specific, highly expressed in skeletal muscle, and at lower levels in cardiac and smooth muscle. Some carriers of Duchenne muscular dystrophy show elevated CA3 levels. The gene spans 10.3 kb and contains seven exons and six introns.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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