Thermo Fisher Scientific PTGES2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunocytochemistry (ICC/IF)

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 88-377 of human PTGES2 (NP_079348.1). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PTGES2,uniProtId:Q9H7Z7-1,ncbiNodeId:9606,antigenRange:88-377,antigenLength:377,antigenImageFileName:PA5-120215_PTGES2_Q9H7Z7-1_Rabbit.svg,antigenImageFileNamePDP:PA5-120215_PTGES2_Q9H7Z7-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

2.72 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2913787

Product Specific Information

Positive test controls include: 293T, HeLa, BT-474, HL-60, Rat brain. The target is usually found in the following locations: Cytoplasm, Golgi apparatus membrane, Single-pass membrane protein, perinuclear region.

Immunogen sequence: ERSAAQLSLS SRLQLTLYQY KTCPFCSKVR AFLDFHALPY QVVEVNPVRR AEIKFSSYRK VPILVAQEGE SSQQLNDSSV IISALKTYLV SGQPLEEIIT YYPAMKAVNE QGKEVTEFGN KYWLMLNEKE AQQVYGGKEA RTEEMKWRQW ADDWLVHLIS PNVYRTPTEA LASFDYIVRE GKFGAVEGAV AKYMGAAAMY LISKRLKSRH RLQDNVREDL YEAADKWVAA VGKDRPFMGG QKPNLADLAV YGVLRVMEGL DAFDDLMQHT HIQPWYLRVE RAITEASPAH

Target Information

The PTGES2 gene encodes for the enzyme prostaglandin E synthase 2 (PTGES2), which is crucial for the biosynthesis of prostaglandin E2 (PGE2) from arachidonic acid. This enzyme operates downstream of the cyclooxygenase (COX) pathway, particularly interacting with COX-1 and COX-2 enzymes. PTGES2 is involved in various physiological and pathological processes by generating PGE2, which functions in inflammation, fever generation, and pain. Notably, PTGES2 is a membrane-associated protein and is distinct in its role compared to other prostaglandin synthases due to its specific functional and regulatory properties. Its activity is essential in fine-tuning the levels of PGE2 in tissues, impacting numerous signaling cascades, including those involved in immune responses and vascular functions.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.