Thermo Fisher Scientific PTGES2 Polyclonal Antibody
Rabbit polyclonal antibody targeting human PTGES2, validated for WB, ICC/IF, and ELISA applications. High purity (Affinity Chromatography) and concentrated liquid form (2.72 mg/mL). Suitable for detecting PTGES2 in cytoplasm and Golgi membrane. For res...
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 88–377 of human PTGES2 (NP_079348.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.72 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2913787 |
Product Specific Information
Positive test controls include: 293T, HeLa, BT-474, HL-60, Rat brain.
Target localization: Cytoplasm, Golgi apparatus membrane, Single-pass membrane protein, perinuclear region.
Immunogen sequence:
ERSAAQLSLS SRLQLTLYQY KTCPFCSKVR AFLDFHALPY QVVEVNPVRR AEIKFSSYRK VPILVAQEGE SSQQLNDSSV IISALKTYLV SGQPLEEIIT YYPAMKAVNE QGKEVTEFGN KYWLMLNEKE AQQVYGGKEA RTEEMKWRQW ADDWLVHLIS PNVYRTPTEA LASFDYIVRE GKFGAVEGAV AKYMGAAAMY LISKRLKSRH RLQDNVREDL YEAADKWVAA VGKDRPFMGG QKPNLADLAV YGVLRVMEGL DAFDDLMQHT HIQPWYLRVE RAITEASPAH
Target Information
The PTGES2 gene encodes prostaglandin E synthase 2 (PTGES2), an enzyme essential for prostaglandin E2 (PGE2) biosynthesis from arachidonic acid. Operating downstream of the COX pathway, PTGES2 interacts with COX-1 and COX-2 and plays a key role in inflammation, fever, and pain regulation. It is a membrane-associated protein distinct from other prostaglandin synthases in function and regulation, contributing to PGE2 level modulation and signaling in immune and vascular processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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