Thermo Fisher Scientific TP53I3 Monoclonal Antibody (OTI3E3), TrueMAB
TP53I3 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot에 적합합니다. 인간 반응성, 비결합형 형태이며 PBS 저장용액에 동결건조되어 제공됩니다. 연구용으로만 사용 가능하며 p53 매개 세포 사멸 연구에 활용됩니다.
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Thermo Fisher Scientific TP53I3 Monoclonal Antibody (OTI3E3), TrueMAB
Applications
- Western Blot (WB)
Tested Dilution
- 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3E3 |
| Immunogen | Full length human recombinant protein of TP53I3 produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
TP53I3 encodes a protein similar to oxidoreductases involved in cellular responses to oxidative stress and irradiation. It is induced by tumor suppressor p53 and participates in p53-mediated cell death.
The gene promoter contains a p53 consensus binding site and a downstream pentanucleotide microsatellite sequence. The polymorphic microsatellite correlates with transcriptional activation by p53 and may influence cancer susceptibility.
At least two transcript variants encoding the same protein have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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