Thermo Fisher Scientific MIA3/TANGO Polyclonal Antibody
MIA3/TANGO 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunoprecipitation에 사용 가능. 인간 MIA3 단백질 350–400번 잔기 영역을 면역원으로 제작. 1 mg/mL 농도의 액상 형태로 4°C 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 350–400 of human Melanoma inhibitory activity protein 3 (MIA3) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
Target Information
MIA3 plays a role in the transport of cargos too large for COPII-coated vesicles, facilitating their incorporation into membrane-bound carriers for export from the endoplasmic reticulum. It is essential for collagen VII (COL7A1) secretion and may assist in cargo loading at ER exit sites by interacting with COPII coat subunits Sec23/24. MIA3 is specific to COL7A1 cargo but may also contribute to secretion of other proteins, including lipoproteins. It is required for proper assembly of COPII coat components and localization of SEC16A and ER-resident complexes (MIA2 and PREB/SEC12) to ER exit sites. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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