Thermo Fisher Scientific PPAR delta Polyclonal Antibody
PPAR delta 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, 다양한 종(Human, Mouse, Rat)에 반응. WB, IHC, ICC, Flow, ELISA 등 다중 응용 가능. 고순도 Protein A 정제 및 안정한 액상 형태로 연구용 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:20–1:100 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from mouse PPAR-delta, amino acids 2–100 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. PPARs are nuclear hormone receptors that bind peroxisome proliferators and regulate peroxisome production. They mediate various biological processes and may be involved in chronic diseases such as diabetes, obesity, atherosclerosis, and cancer.
PPAR delta acts as a potent inhibitor of ligand-induced transcription activity of PPAR alpha and PPAR gamma, functioning as an integrator of transcription repression and nuclear receptor signaling. Elevated expression of this gene has been found in colorectal cancer cells and can be repressed by the tumor suppressor protein APC. Mouse knockout studies suggest roles in myelination of the corpus callosum, lipid metabolism, and epidermal cell proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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