Thermo Fisher Scientific PDE3A Polyclonal Antibody
Rabbit polyclonal antibody against human PDE3A. Validated for IHC(P) at 20 µg/mL. High specificity and affinity purified. Suitable for research use only. Stable at 4°C short term or -20°C long term.
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Applications
Immunohistochemistry (Paraffin) [IHC (P)]
- Tested Dilution: 20 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 18 amino acid peptide from N-terminus of human PDE3A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550434 |
Product Specific Information
Percent identity with other species by BLAST analysis:
- Human (100%)
- Gibbon, Monkey (94%)
- Horse (83%)
For IHC(P), use heat-induced antigen retrieval in pH 6.0 citrate buffer.
After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
Target Information
Cyclic nucleotide phosphodiesterases (PDEs) comprise a complex group of enzymes, and at least five major PDE families or classes with distinctive properties have been identified.
Members of the cGMP-inhibited cAMP PDE (cGI-PDE) family, such as PDE3A, are characterized by high affinity for cAMP and cGMP and competitive inhibition of their cAMP hydrolytic activity by cGMP and certain positive inotropic agents (Meacci et al., 1992 [PubMed 1315035]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: PA5-32973_PDE3A_Q14432-1_Rabbit_PDP.jpeg, PA5-32973_PDE3A_Q14432-1_Rabbit.svg)
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