Thermo Fisher Scientific PDE7B Polyclonal Antibody
PDE7B 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P) 실험에 적합합니다. Human 및 Non-human primate 반응성이 있으며, 항원 친화 크로마토그래피로 정제되었습니다. 장기 보관 시 -20°C에서 보관을 권장합니다.
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- PA532977
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Applications and Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 1.25–2.5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 18 amino acid peptide from internal region of human PDE7B |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.32 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550438 |
Product Specific Information
Percent identity with other species by BLAST analysis:
- Human, Gorilla, Gibbon, Monkey, Marmoset: 100%
- Mouse, Rat, Bovine, Dog, Bat, Hamster, Elephant, Panda, Horse, Rabbit, Pig, Turkey, Chicken: 94%
- Platypus: 89%
For IHC(P), use heat-induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
Target Information
The 3’,5’-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3’,5’-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5’-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a cAMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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