
Thermo Fisher Scientific PDE3A Polyclonal Antibody
PDE3A 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, IHC(P) 실험에 적합합니다. Horse, Human, Mouse 등 다양한 종에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS에 0.1% sodium azide가 포함되어 있습니다.
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Applications and Tested Dilution
- Immunohistochemistry (Paraffin) [IHC (P)]: 20 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Horse, Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 17 amino acid peptide from internal region of human PDE3A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550432 |
Product Specific Information
- Percent identity with other species by BLAST analysis:
Human, Gibbon, Monkey, Mouse, Rat, Horse, Opossum (100%); Chicken (88%) - For IHC(P), use heat-induced antigen retrieval in pH 6.0 citrate buffer.
After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
Target Information
Cyclic nucleotide phosphodiesterases (PDEs) comprise a complex group of enzymes, and at least five major PDE families or classes with distinctive properties have been identified. Members of the cGMP-inhibited cAMP PDE (cGI-PDE) family, such as PDE3A, are characterized by high affinity for cAMP and cGMP and competitive inhibition of their cAMP hydrolytic activity by cGMP and certain positive inotropic agents (Meacci et al., 1992 [PubMed 1315035]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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