
Thermo Fisher Scientific PDE2A Polyclonal Antibody
PDE2A 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P) 실험에 적합합니다. Human, Dog, Horse 등에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 1 mg/mL 농도이며, 단기 4°C, 장기 -20°C 보관이 권장됩니다.
- 카탈로그번호
- PA532970
- 판매단위
- pk
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Applications
Immunohistochemistry (Paraffin) [IHC (P)]
- Tested Dilution: 20 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Horse, Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 17 amino acid peptide from N-terminus of human PDE2A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage conditions | Store at 4°C (short term); for long term, store at -20°C, avoiding freeze/thaw cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550431 |
Product Specific Information
Percent identity with other species (BLAST analysis):
Human, Gorilla, Marmoset, Dog, Panda, Horse (100%);
Gibbon, Monkey, Mouse, Rat, Bovine, Elephant, Rabbit (94%);
Pig (88%).For IHC(P), use heat-induced antigen retrieval in pH 6.0 citrate buffer.
After incubation with the primary antibody, slides should be incubated with a biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
Target Information
PDE2A (phosphodiesterase 2A) is a 100 kD cyclic nucleotide phosphodiesterase (PDE).
Three isoforms (PDE2A1, PDE2A2, PDE2A3) arise from a single gene via alternative splicing.
PDE2A degrades both cAMP and cGMP, with higher efficacy for cGMP.
It is expressed in various tissues, with the highest levels in the brain (cerebellum and neocortex).
PDE2A has been implicated in penile erectile dysfunction and in regulating fluid and inflammatory cell transport across the endothelial barrier.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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