Thermo Fisher Scientific ADAMTS13 Polyclonal Antibody
ADAMTS13 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 폴리클로날 항체. Western blot 및 Immunoprecipitation에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, 4°C에서 보관. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Assay-dependent
Immunoprecipitation (IP)
- 1–5 µg/µL serum
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 150 and 200 of human ADAMTS13 (a disintegrin-like and metalloprotease with thrombospondin type 1 motif, 13) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
ADAMTS13 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of this family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members differ in the number of C-terminal TS motifs, and some have unique C-terminal domains.
The enzyme functions as the von Willebrand Factor (vWF)-cleaving protease, responsible for cleaving at the site of Tyr842–Met843 of the vWF molecule. A deficiency of this enzyme is associated with thrombotic thrombocytopenic purpura (TTP).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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