Thermo Fisher Scientific ADAMTS13 Polyclonal Antibody
ADAMTS13 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 다클론 항체. Western blot 및 Immunoprecipitation에 적합. 인간 및 영장류 반응성. 액상 형태, 항원 친화 크로마토그래피로 정제, 4°C 보관.
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Thermo Fisher Scientific ADAMTS13 Polyclonal Antibody
Applications
- Western Blot (WB): Assay-dependent
- Immunoprecipitation (IP): 1–5 µg/µL serum
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 75 and 125 of human ADAMTS13 (a disintegrin-like and metalloprotease with thrombospondin type 1 motif, 13) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, antibody predicted to react with Orangutan, Gorilla, and Chimpanzee
Target Information
ADAMTS13 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif.
Individual members differ in the number of C-terminal TS motifs and may have unique C-terminal domains.
The enzyme acts as the von Willebrand Factor (vWF)-cleaving protease, responsible for cleavage at Tyr842–Met843 of the vWF molecule.
A deficiency of this enzyme is associated with thrombotic thrombocytopenic purpura.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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