Thermo Fisher Scientific Synaptophysin Polyclonal Antibody
Rabbit polyclonal antibody against Synaptophysin for WB and IHC(P) applications. Recognizes a synthetic peptide from rat Synaptophysin. Lyophilized form, reconstitutable with sterile water. Suitable for neuronal and neuroendocrine marker studies.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:10,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:3,000 |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from rat Synaptophysin conjugated to blue carrier protein was used as the antigen. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2240186 |
Product Specific Information
- Glycerol (1:1) may be added for additional stability.
- Reconstitute with 100 µL of sterile water.
Target Information
Synaptophysin is a calcium-binding integral membrane glycoprotein present in presynaptic vesicles in almost all neurons. It has four transmembrane domains and forms a complex with dynamin at high calcium concentrations, suggesting involvement in synaptic vesicle endocytosis. Synaptophysin also plays roles in short- and long-term synaptic plasticity. It is widely used as a marker for nerve terminals and for differentiating neuroendocrine tumors. Mutations in the gene can result in mental retardation, X-linked 96.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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