Thermo Fisher Scientific PYY Polyclonal Antibody, Biotin

Applications

ELISA (ELISA)

• Tested Dilution: 1:2,000–1:10,000

Product Specifications

Product Specific Information

• Catalog No.: PA1-9590
• Detects PYY in human, mouse, and rat samples.
• Validated for use in ELISA applications.
• Immunogen: Synthetic peptide corresponding to amino acids 3–18 (I K P E A P G E D A S P E E L N) of human PYY.

Target Information

Peptide tyrosine-tyrosine amide (3–36), or PYY (3–36), is a major metabolite of the gut hormone PYY. It is produced by the action of dipeptidyl peptidase IV on PYY in the intestinal brush border and in the circulation. PYY (3–36) is a potent inhibitor of food intake in rats and humans, acting selectively on the Y2 receptor to inhibit orexigenic NPY neurons in the arcuate nucleus, thereby disinhibiting anorexigenic POMC neurons. The anorexigenic effect of PYY (3–36) is additive to that of the co-secreted gut hormone GLP-1.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.