Thermo Fisher Scientific PYY Polyclonal Antibody, Biotin

Applications

Tested Dilution

Publications

ELISA (ELISA)

1:2,000-1:10,000

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Chicken / IgY

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide corresponding to amino acids 3-18 of human PYY. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PYY,uniProtId:P10082-1,ncbiNodeId:9606,antigenRange:3-18,antigenLength:97,antigenImageFileName:PA1-9590_PYY_P10082-1_Chicken.svg,antigenImageFileNamePDP:PA1-9590_PYY_P10082-1_Chicken_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Biotin Biotin Biotin

Form

Liquid

Concentration

0.5 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2284577

Product Specific Information

PA1-9590 detects PYY in human, mouse and rat samples.

PA1-9590 has been successfully used in ELISA procedures.

PA1-9590 immunogen is a synthetic peptide corresponding to amino acids 3-18 (I K P E A P G E D A S P E E L N) of human PYY.

Target Information

Peptide tyrosine-tyrosine amide (3-36), or PYY (3-36), is a major metabolite of the gut hormone PYY and is produced by the action of dipeptidyl peptidase IV on PYY in the intestinal brush border and in the circulation. PYY (3-36) is a potent inhibitor of food intake in rats and humans, acting selectively on the Y2 receptor to inhibit orexigenic NPY neurons in the arcuate nucleus, thus disinhibiting anorexigenic POMC neurons. The anorexigenic effect of PYY (3-36) is additive to that of the co-secreted gut hormone GLP-1.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.