Thermo Fisher Scientific PYY Polyclonal Antibody
Human, Mouse, Rat 시료에서 PYY 단백질 검출용 다클론 항체. ELISA에 최적화되어 있으며, 합성 펩타이드(aa 3-18) 면역원으로 제작됨. IgY 형식의 Chicken 유래 항체로, 0.5 mg/mL 농도의 액상 형태. 4°C 단기 보관, -20°C 장기 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| ELISA | 1:2,000–1:5,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Chicken / IgY |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 3–18 of human PYY |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C (short term); for long term, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2172984 |
Product Specific Information
- PA1-9582 detects PYY in human, mouse, and rat samples.
- Successfully used in ELISA procedures.
- Immunogen: synthetic peptide corresponding to amino acids 3–18 of human PYY (IKPEAPGEDASPEELN).
Target Information
Peptide tyrosine-tyrosine amide (3–36), or PYY (3–36), is a major metabolite of the gut hormone PYY and is produced by the action of dipeptidyl peptidase IV on PYY in the intestinal brush border and in the circulation.
PYY (3–36) is a potent inhibitor of food intake in rats and humans, acting selectively on the Y2 receptor to inhibit orexigenic NPY neurons in the arcuate nucleus, thus disinhibiting anorexigenic POMC neurons.
The anorexigenic effect of PYY (3–36) is additive to that of the co-secreted gut hormone GLP-1.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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