Thermo Fisher Scientific OCT1 Polyclonal Antibody
OCT1 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot에 최적화됨. Human 및 Rat 시료 반응성. Affinity chromatography로 정제된 액상 항체로, -20°C에서 보관. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human SLC22A1 (Accession O15245), corresponding to amino acid residues Q60–A80 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852524 |
Product Specific Information
Antibody detects endogenous levels of total OCT1.
Target Information
OCT1 (POU2F1) is a ubiquitously expressed transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates promoters of genes such as small nuclear RNAs (snRNA), histone H2B, and immunoglobulins. It modulates transcription transactivation by NR3C1, AR, and PGR.
During human herpes simplex virus (HSV) infection, POU2F1 forms a multiprotein-DNA complex with the viral transactivator protein VP16 and HCFC1, enabling transcription of viral immediate early genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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