Thermo Fisher Scientific SIRT3 Monoclonal Antibody (K.830.1)
SIRT3 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, Western blot, IHC, ICC/IF, IP 등 다양한 분석에 사용 가능. 인간, 비인간 영장류, 랫트 반응성. 고순도 액상 형태로 -20°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Immunoprecipitation (IP) | 1:50 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | K.830.1 |
| Immunogen | Synthetic peptide corresponding to the sequence of human SirT3 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 73 µg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 50% glycerol, 0.15M NaCl, 100µg/mL BSA |
| Contains | <0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_10980823 |
Product Specific Information
- It is not recommended to aliquot this antibody.
- This antibody is not cross-reactive with other sirtuins.
Target Information
SIRT3 is a member of the sirtuin family of proteins, homologous to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes.
The functions of human sirtuins have not yet been fully determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity.
SIRT3 belongs to class I of the sirtuin family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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