Thermo Fisher Scientific LOX Monoclonal Antibody (OTI3C3), TrueMAB
인간 LOX 단백질(aa 22-168)을 면역원으로 제작된 마우스 단클론 항체. Western blot과 ICC/IF에 적합하며, 고순도의 친화 크로마토그래피 정제 제품. 동결건조 형태로 제공되며, PBS 완충액(8% 트레할로스) 포함. 종양 억제 및 세포 이동 연구에 활용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3C3 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 22–168 of human LOX produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Lysyl oxidase (LOX) is a copper-containing amine oxidase that oxidizes primary amine substrates to reactive aldehydes.
It plays a crucial role in the formation and repair of the extracellular matrix and exhibits multifunctional biological roles including developmental regulation, tumor suppression, cell motility, and cellular senescence.
The secreted form of LOX contributes to the invasive properties of hypoxic human cancer cells, making it an important therapeutic target for preventing and treating metastasis.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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