Thermo Fisher Scientific FIG4 Polyclonal Antibody
Rabbit polyclonal antibody against human FIG4 protein. Recombinant immunogen, unconjugated form, suitable for research use only. High sequence identity with mouse (99%) and rat (97%) orthologs. Liquid format, stored at 4°C short term or -20°C long term.
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Thermo Fisher Scientific FIG4 Polyclonal Antibody
제품 사양
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human FIG4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2664269 |
Product Specific Information
Immunogen sequence:
VKEREKRKHER ILSEELVAAV TYLNQFLPPE HTIVYIPWDM AKYTKSKLCN VLDRLNVIAE SVVKKTGFFV NRPDSYCSIL RPDEKWNELG GCVIPTGR
Highest antigen sequence identity to the following orthologs:
- Mouse: 99%
- Rat: 97%
Target Information
The protein encoded by this gene belongs to the SAC domain-containing protein family.
The SAC domain (approximately 400 amino acids) consists of seven conserved motifs and exhibits phosphoinositide phosphatase activity.
The yeast homolog Sac1p regulates various phosphoinositides and impacts cellular functions such as:
- Actin cytoskeleton organization
- Golgi function
- Vacuole morphology maintenance
Membrane-bound phosphoinositides serve as signaling molecules and play a key role in vesicle trafficking in eukaryotic cells.
Mutations in this gene are associated with Charcot-Marie-Tooth disease type 4J.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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