Thermo Fisher Scientific FGFR5 Polyclonal Antibody
Human FGFR5 단백질을 인식하는 Rabbit Polyclonal Antibody로, ICC/IF에 적합하며 항원 친화 크로마토그래피로 정제됨. 0.2 mg/mL 농도의 액상 형태로 제공되며, PBS 기반 버퍼에 저장. 연구용으로 FGFR5 관련 세포 성장 인자 연구에 활용 가능.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
- Publications: [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human FGFR5 (Control fragment: Product #RP-107656) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long-term, store at -20°C (avoid freeze/thaw cycles) |
| Shipping Conditions | Wet ice |
| RRID | AB_2664042 |
Product Specific Information
- Immunogen Sequence:
KATNGFGSLSV NYTLVVLDDI SPGKESLGPD SSSGGQEDPA SQQWARPRFT QPSKMRRRVI ARPVGSSVRL KCVAS - Sequence Identity:
Highest antigen sequence identity to orthologs — mouse 92%, rat 89%.
Target Information
Acidic and basic fibroblast growth factors (FGFs) are multifunctional polypeptide growth factors that stimulate proliferation of mesenchymal, epithelial, and neuro-ectodermal cells. FGFs act by binding and activating specific cell surface receptors. Six FGF receptor family members have been identified: FGFR-1 (Flg), FGFR-2 (BEK), FGFR-3, FGFR-4, FGFR-5, and FGFR-6.
FGFR-5 lacks the cytoplasmic kinase domain and is expressed in various tissues including kidney, brain, and lung, with preferential expression in pancreas, suggesting a role in pancreatic function regulation.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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