Thermo Fisher Scientific PTEN-P1 Polyclonal Antibody
Human PTEN-P1 단백질을 인식하는 친화 정제된 rabbit polyclonal 항체로, Western blot, ELISA, Immunoprecipitation에 적합합니다. PTEN 관련 종양 억제 연구용으로 사용되며, -20°C에서 안정적으로 보관 가능합니다.
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Thermo Fisher Scientific PTEN-P1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:3,000 |
| ELISA | 1:160,000 |
| Immunoprecipitation (IP) | 1:500–1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide corresponding to amino acids near the N-terminal end of human PTEN-P1 protein. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.15 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.02M potassium phosphate, pH 7.2, with 0.15M NaCl |
| Contains | 0.01% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature.
This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use.
This affinity-purified antibody is directed against human PTEN protein. Reactivity occurs against human PTEN protein.
BLAST analysis suggests cross-reactivity with PTEN proteins from mouse and dog sources based on 82% homology with the immunizing sequence. Reactivity against homologues from other sources is not known.
Target Information
PTENP1 represents a highly homologous processed pseudogene of PTEN (phosphatase and tensin homolog), a tumor suppressor protein that negatively regulates the AKT/PKB signaling pathway.
PTENP1 is located on chromosome 9 and regulates PTEN through both sense and antisense RNAs (Gene ID: 101243555).
This long non-coding RNA (lncRNA) acts as a decoy for PTEN-targeting microRNAs and exhibits tumor suppressive activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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