Thermo Fisher Scientific CCR8 Polyclonal Antibody
CCR8 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에 적합하며 인간 CCR8(183-201) 잔기 기반 합성 펩타이드로 면역화됨. 액상 형태로 제공되며 -20°C에서 보관. 연구용으로만 사용 가능.
- 카탈로그번호
- PA112539
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues 183–201 of human CCR8 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1071069 |
Product Specific Information
A suggested positive control for this product is human spleen lysate.
Target Information
CCR8 encodes a member of the beta chemokine receptor family, predicted to be a seven-transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors play key roles in the migration of various cell types to inflammatory sites.
This receptor is preferentially expressed in the thymus, and its known ligands include I-309, TARC (thymus activation-regulated cytokine), and MIP-1β (macrophage inflammatory protein-1 beta).
Studies suggest CCR8’s involvement in monocyte chemotaxis and thymic cell apoptosis, contributing to proper positioning of activated T cells within antigenic challenge sites and lymphoid tissues.
CCR8 expression has been reported in spleen, thymus, natural killer cells, monocytes, and T cells, with lower levels in peripheral blood leukocytes.
This gene is located in the chemokine receptor gene cluster region.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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