Thermo Fisher Scientific CX3CR1 Polyclonal Antibody
CX3CR1 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western Blot에 적합합니다. Synthetic peptide(175-189 aa)를 면역원으로 제작되었으며, 액상 형태로 제공됩니다. HIV 연구 및 면역세포 이동 관련 연구에 활용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.5–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues 175–189 of human CX3CR1 receptor |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.0 mg/mL |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1073934 |
Product Specific Information
A suggested positive control for this product is THP-1 cell lysate.
Target Information
CX3CR1 is one of the chemokine receptors required as a coreceptor for HIV infection. The genes encoding human, mouse, and rat CX3CR1 were cloned and designated V28 and CMKBRL1, CX3CR1, and RBS11, respectively. The encoded seven-transmembrane protein was identified as the receptor for fractalkine and renamed CX3CR1. CX3CR1 serves as a coreceptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by fractalkine. It mediates leukocyte migration and adhesion and is expressed in various human tissues and cell lines.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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