Thermo Fisher Scientific CPS1 Polyclonal Antibody
CPS1 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot 및 면역세포염색에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 인간, 마우스, 랫트 시료에 반응합니다. 고순도 액상 형태로 장기 보관 시 -20°C에서 안정적으로 유지됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:100–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein of human CPS1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2720066 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is greater than 95% as determined by SDS-PAGE.
Target Information
The mitochondrial enzyme encoded by the CPS1 gene catalyzes the synthesis of carbamoyl phosphate from ammonia and bicarbonate. This reaction is the first committed step of the urea cycle, essential for the removal of excess urea from cells. The encoded protein may also function as a core mitochondrial nucleoid protein. Three transcript variants encoding different isoforms have been identified; the shortest isoform may not localize to the mitochondrion. Mutations in this gene are associated with carbamoyl phosphate synthetase deficiency, susceptibility to persistent pulmonary hypertension, and venoocclusive disease following bone marrow transplantation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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