Thermo Fisher Scientific MYC Monoclonal Antibody (OTI5E9G2), TrueMAB
MYC 단백질을 인식하는 Mouse IgG2a 단일클론 항체로 Western Blot 및 Immunocytochemistry에 적합. 인간, 개, 쥐 반응성. 고순도 Affinity chromatography 정제, 1 mg/mL 농도. 세포주기 조절 및 암 연구용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:200–1:4000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human, Rat |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5E9G2 |
| Immunogen | Full length human recombinant protein of human Myc produced in 293T |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Myc is a proto-oncogene encoding a nuclear phosphoprotein involved in cell cycle progression, apoptosis, and cellular transformation.
The protein forms a heterodimer with the transcription factor MAX, binding to the E-box DNA consensus sequence to regulate transcription of target genes.
Amplification of MYC is frequently observed in various human cancers, and translocations involving MYC are associated with Burkitt lymphoma and multiple myeloma.
Translation initiates from both an upstream non-AUG (CUG) and a downstream AUG start site, producing two isoforms with distinct N-termini.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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