Thermo Fisher Scientific PAAF1 Monoclonal Antibody (OTI1F11), TrueMAB
PAAF1 단백질을 인식하는 Mouse 모노클로날 항체로 Western blot과 Immunocytochemistry에 사용 가능. 고순도 Affinity chromatography 정제, 1 mg/mL 농도. PBS/BSA/glycerol 완충액에 보관되며 -20°C에서 안정적 보관 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:400–1:4,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1F11 |
| Immunogen | Full length human recombinant protein of human PAAF1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
PAAF1 inhibits proteasome 26S assembly and proteolytic activity by impairing the association of the 19S regulatory complex with the 20S core.
In case of HIV-1 infection, it is recruited by viral Tat to the HIV-1 promoter, promoting the recruitment of the 19S regulatory complex through dissociation of the proteasome 26S.
This presumably enhances provirus transcription efficiency.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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