Thermo Fisher Scientific pro-Brain Natriuretic Peptide Monoclonal Antibody (24E11)
인간 proBNP를 검출하는 Thermo Fisher Scientific의 단클론 항체(클론 24E11). ELISA 및 Western blot에 적합하며, 높은 특이성과 안정성을 제공. Protein A로 정제된 액상 형태로 4°C 보관.
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Applications
Western Blot (WB)
- Tested Dilution: Assay-dependent
ELISA
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 24E11 |
| Immunogen | Synthetic peptide corresponding to residues R(61) G H R K M V L Y T L R A P R(76) of human proBNP |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 5.2 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_560695 |
Product Specific Information
MA1-20631 detects proBNP in human samples.
Target Information
In cardiac tissue, brain natriuretic peptide (BNP) is synthesized as a 134 amino acid precursor (prepro-BNP), which is cleaved by proteases to form a 26 aa signal peptide and a 108 aa pro-BNP.
Proteolytic digestion of pro-BNP results in formation of 76 aa amino-terminal NT-proBNP and biologically active 32 aa BNP hormone molecule.
Both proBNP and NT-proBNP circulate in human plasma and have been proposed as markers for early diagnosis of left ventricular dysfunction as well as prognostic markers of possible cardiac complications in patients with heart failure.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: MA1-20631_pro-Brain_Natriuretic_Peptide_P16860-1_House_mouse.svg)
(이미지: MA1-20631_pro-Brain_Natriuretic_Peptide_P16860-1_House_mouse_PDP.jpeg)
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