Thermo Fisher Scientific pro-Brain Natriuretic Peptide Monoclonal Antibody (5B6)
인간 proBNP를 인식하는 단클론 항체로, Western blot 및 ELISA에 적합합니다. 단백질 A로 정제된 액상 항체이며 5 mg/mL 농도로 제공됩니다. 심부전 관련 바이오마커 연구용으로 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: Assay-dependent
ELISA
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5B6 |
| Immunogen | Synthetic peptide corresponding to residues H(1) P L G S P G S A S D L(12) of human proBNP |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_560693 |
Product Specific Information
MA1-20622 detects proBNP in human samples.
Target Information
In cardiac tissue, brain natriuretic peptide (BNP) is synthesized as a 134 amino acid precursor (prepro-BNP), which is cleaved by proteases to form a 26 amino acid signal peptide and a 108 amino acid pro-BNP.
Proteolytic digestion of pro-BNP results in formation of a 76 amino-terminal NT-proBNP and a biologically active 32 amino acid BNP hormone molecule.
Both proBNP and NT-proBNP circulate in human plasma and have been proposed as markers for early diagnosis of left ventricular dysfunction as well as prognostic markers of possible cardiac complications in patients with heart failure.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: MA1-20622_pro-Brain_Natriuretic_Peptide_P16860-1_House_mouse.svg, MA1-20622_pro-Brain_Natriuretic_Peptide_P16860-1_House_mouse_PDP.jpeg)
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