Thermo Fisher Scientific MEK2 Polyclonal Antibody
Thermo Fisher Scientific의 MEK2 Polyclonal Antibody는 Rabbit IgG 기반 항체로, Mouse 시료에서 반응하며 WB 및 ELISA에 적합합니다. MEK2 단백질의 세린/트레오닌 키나아제 활성 연구에 활용되며, 액상 형태로 안정적인 보관이 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 1–100 of human MEK2 (NP_1095871) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.81 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804113 |
Product Specific Information
- Positive Samples: Mouse brain
- Cellular Location: Cytoplasm, Membrane, Peripheral membrane protein
- Immunogen Sequence:
MLARRKPVLP ALTINPTIAE GPSPTSEGAS EANLVDLQKK LEELELDEQQ KKRLEAFLTQ KAKVGELKDD DFERISELGA GNGGVVTKVQ HRPSGLIMAR
Target Information
MAP2K2 (MEK2) is a dual specificity serine/threonine kinase involved in mitogen growth factor signal transduction.
MEK2 (MAPKK2) activates ERK1/2 and MAPK enzymes by phosphorylating residues within the threonine/glutamate/tyrosine (TEY) motif.
MEK1 and MEK2 are activated by dual phosphorylation on serine 218 and 222 in the activation loop.
Threonine 292 of MEK1 is phosphorylated by ERK2, forming a negative feedback loop that suppresses MEK1 activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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