Thermo Fisher Scientific RASGRP3 Monoclonal Antibody (OTI2C11), TrueMAB
RASGRP3 단백질을 인식하는 Mouse IgG2a 단클론 항체로 Western Blot 및 IHC(P) 검증 완료. Human 반응성, Lyophilized 형태로 제공되며 보존제가 없음. 신호전달 연구 및 RAS 활성화 기전 분석에 적합.
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Applications
- Western Blot (WB): 1:2,000
- Immunohistochemistry (Paraffin) (IHC (P)): 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2C11 |
| Immunogen | Human recombinant protein fragment (aa 380–690 of RASGRP3) produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final concentration of approximately 1 mg/mL.
For conjugation experiments, perform desalting using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Members of the RAS subfamily of GTPases act as GTP/GDP-regulated molecular switches.
Guanine nucleotide exchange factors (GEFs), such as RASGRP3, activate RAS by promoting GTP binding, serving as a key link between cell surface receptors and RAS activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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