Thermo Fisher Scientific Ezrin Polyclonal Antibody
Ezrin 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot에 최적화됨. 다양한 종(Bovine, Human, Mouse 등)에 반응. Antigen affinity chromatography로 정제된 액상 형태. 세포막-세포골격 연결 연구에 적합.
- 카탈로그번호
- PA517767
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Dog, Human, Mouse, Non-human primate, Rat, Xenopus |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the residues surrounding Thr567 of human ezrin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 9 ng/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage conditions | -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11005047 |
Product Specific Information
- It is not recommended to aliquot this antibody.
- This antibody is not cross-reactive with related proteins such as merlin or band 4.
Target Information
The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli.
As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton.
It plays a key role in cell surface structure adhesion, migration, and organization, and has been implicated in various human cancers.
A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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