Thermo Fisher Scientific Phospho-VASP (Ser157) Polyclonal Antibody
VASP 단백질의 Ser157 인산화 부위를 인식하는 폴리클로날 항체로, Western blot에 적합합니다. 다양한 종(인간, 마우스, 랫 등)에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며, -20°C에서 보관합니다.
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Applications
- Western Blot (WB): Tested dilution 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Guinea pig, Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic phosphopeptide corresponding to residues surrounding pSer157 of human VASP |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 73 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 50% glycerol, 100 µg/mL BSA |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10986176 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. These proteins contain an EVH1 N-terminal domain that binds proteins with E/DFPPPPXD/E motifs, targeting them to focal adhesions. The mid-region has a proline-rich domain that interacts with SH3 and WW domain-containing proteins, while the C-terminal EVH2 domain mediates tetramerization and binds G and F actin. VASP is associated with filamentous actin formation and plays a key role in cell adhesion and motility. It may also participate in intracellular signaling pathways regulating integrin-extracellular matrix interactions. VASP is regulated by cyclic nucleotide-dependent kinases PKA and PKG.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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