Thermo Fisher Scientific SPAG4 Monoclonal Antibody (OTI3E9), TrueMAB

Applications

• Western Blot (WB): Tested dilution 1:500

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of ~1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).

Target Information

The mammalian sperm flagellum contains two cytoskeletal structures associated with the axoneme: the outer dense fibers (midpiece and principal piece) and the fibrous sheath (principal piece of the tail).
Defects in these structures are linked to abnormal tail morphology, reduced sperm motility, and infertility.
In rats, the SPAG4 protein associates with an outer dense fiber protein via a leucine zipper motif and localizes to the microtubules of the manchette and axoneme during sperm tail development.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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