Thermo Fisher Scientific RPS6KA2 Monoclonal Antibody (OTI5G2), TrueMAB
RPS6KA2 단백질을 인식하는 Mouse IgG1 단클론 항체로, WB에 1:500 희석으로 사용 가능. Human, Mouse, Rat 반응성. Lyophilized 형태로 제공되며 PBS buffer와 trehalose 포함. 연구용으로 성장인자 신호전달 관련 분석에 적합.
- 카탈로그번호
- CF809874
- 판매단위
- pk
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Applications
- Western Blot (WB): Tested dilution 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5G2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–51 of human RPS6KA2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional round of desalting using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
RPS6KA2 (RSK3) serine/threonine kinase is a member of the ribosomal S6 kinase (RSK) family. It acts as a signal-transducing intermediate in the cellular response to various growth factors. Expressed in many tissues, with higher levels in lung and skeletal muscle. The RSK1–4 proteins are downstream members of the ERK/MAPK cascade. Loss of RSK2 activity in humans leads to Coffin-Lowry syndrome, characterized by mental retardation and growth deficits, and may influence G-protein coupled signaling regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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