
Thermo Fisher Scientific RPS6KA2 Monoclonal Antibody (OTI2H3), TrueMAB
RPS6KA2 단백질을 인식하는 단클론 항체로, Western blot에 최적화되어 있습니다. Human, Mouse, Rat 시료에 반응하며, 동결건조 형태로 제공됩니다. PBS buffer와 trehalose로 안정화되어 있으며, 연구용으로 적합합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2H3 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–51 of human RPS6KA2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
RPS6KA2 (RSK3) is a serine/threonine kinase belonging to the ribosomal S6 kinase (RSK) family. It acts as a signal transducer in cellular responses to growth factors and is expressed in various tissues, with higher levels in lung and skeletal muscle.
RSK1–4 are downstream members of the ERK/MAPK cascade. Loss of RSK2 activity in humans is associated with Coffin-Lowry syndrome, characterized by mental retardation and growth deficits, and may influence G-protein coupled signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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