Thermo Fisher Scientific RPS6KA2 Monoclonal Antibody (OTI2G5), TrueMAB
RPS6KA2 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot에 1:500 희석으로 사용 가능. 인간, 마우스, 랫트 반응성. 동결건조 형태로 제공되며, PBS/trehalose 버퍼에 보관. 연구용으로 성장인자 신호전달 연구에 적합.
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Applications
- Western Blot (WB): Tested dilution 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2G5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–51 of human RPS6KA2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | –20 °C, avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
RPS6KA2 (RSK3) serine/threonine kinase is a member of the ribosomal S6 kinase (RSK) family. It acts as a signal-transducing intermediate in cellular responses to various growth factors. Expression is found in many tissues, notably in lung and skeletal muscle.
RSK1–4 are downstream members of the ERK/MAPK cascade. Loss of RSK2 activity in humans causes Coffin-Lowry syndrome, characterized by mental retardation and growth deficits, and may influence tonic regulation of G-protein coupled signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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