Thermo Fisher Scientific Phospho-Lyn (Tyr396) Polyclonal Antibody
Phospho-Lyn (Tyr396) 특이 토끼 폴리클로날 항체로, 인산화된 Lyn 단백질 검출에 최적화됨. Western blot에 적합하며 인간에 반응. 항원 친화 크로마토그래피로 정제된 고순도 항체. 단기 4°C, 장기 -20°C 보관 권장.
- 카탈로그번호
- PA578047
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of Human LYN (phospho Tyr396). The exact sequence is proprietary. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.95 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2736390 |
Product Specific Information
- Positive Control: K562
- Predicted Reactivity: Mouse (100%), Rat (100%), Xenopus laevis (100%), Chicken (100%), Sheep (100%), Bovine (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Lyn proto oncogene (Lcl/Yes related novel protein tyrosine kinase) is encoded by the Lyn gene located on chromosome 8 in humans and belongs to the Src family kinase. It is a non-receptor tyrosine kinase that acts as a mediator in transducing cellular signaling. The most well-studied expression of Lyn is in hematopoietic cell types, both lymphoid and myeloid cells, with exclusion in T lymphocytes. Lyn plays diverse roles in regulation of B cell receptor signaling, mast cell signaling, and Epithelial-Mesenchymal Transition (EMT).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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