Thermo Fisher Scientific LRP1 Polyclonal Antibody
LRP1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 최적화됨. 인간, 마우스, 랫드, 치킨 시료에 반응. 항원 친화 크로마토그래피로 정제된 액상 형태이며, 장기 보관 시 -20°C에서 보관. 알츠하이머 관련 연구에 활용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the C-terminus region of human LRP1 (85kDa subunit). The exact sequence is proprietary. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2736100 |
Product Specific Information
- Positive Control: HeLa
- Predicted Reactivity: Mouse (100%), Rat (100%), Chicken (96%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The protein encoded by this gene is an endocytic receptor involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. It is necessary for the A2M-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer’s patients. Expression of this gene decreases with age and is lower in brain tissue from Alzheimer patients compared to controls.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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