Thermo Fisher Scientific TSPY1L Polyclonal Antibody
TSPY1L 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot에 적합. Human 및 Mouse 시료에 반응하며, 항원 친화 크로마토그래피로 정제됨. 액상 형태로 제공되며 2–8°C 보관 권장. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): 0.5–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 20 amino acid peptide near the carboxy terminus of human TSPY1L |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at -20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551835 |
Product Specific Information
- Suggested positive control: A-20 cell lysate
- PA5-34483 can be used with blocking peptide PEP-1525
Target Information
Testis-specific protein on Y chromosome (TSPY1) is an ampliconic gene on the Y chromosome associated with gonadoblastoma. In androgen-dependent testicular germ-cell tumors, TSPY1 can repress the androgen-bound androgen receptor (AR), a member of the nuclear steroid hormone receptor family acting as a ligand-inducible transcription factor. This suggests that TSPY1 functions as a repressor of cell proliferation in germ-cell tumors and possibly in normal gonadal cells during early development. Two isoforms, TSPY1L and TSPY1S, are known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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