Thermo Fisher Scientific SHROOM1 Polyclonal Antibody
SHROOM1 단백질을 인식하는 Thermo Fisher Scientific의 토끼 유래 폴리클로날 항체. 인간, 생쥐, 랫트 반응성. 웨스턴 블롯에 적합하며, 액상 형태로 제공. 신경관 형성과 폐동맥 고혈압 연구에 활용 가능.
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Applications
- Western Blot (WB): 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 16 amino acid peptide near the carboxy terminus of human SHROOM1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long term storage, store at −20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551833 |
Product Specific Information
- Suggested positive control: mouse brain tissue lysate
- PA5-34481 can be used with blocking peptide PEP-1523.
Target Information
SHROOM family members play diverse roles in the development of the nervous system and other tissues.
SHROOM1 is a PDZ domain-containing actin-binding protein required for neural tube morphogenesis.
It facilitates neurulation by regulating the morphology of neuroepithelial cells through apical positioning of an actomyosin network.
SHROOM1 is also expressed in pulmonary arterial smooth muscle cells, and its expression is significantly decreased in mouse and human models of pulmonary arterial hypertension, suggesting a potential link between SHROOM1 expression and pulmonary arterial hypertension.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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